complete dmem media Search Results


complete dulbecco’s modified eagles media c-dmem 400 μm l-arginine 10–013-cv  (Cellgro)
90
Cellgro complete dulbecco’s modified eagles media c-dmem 400 μm l-arginine 10–013-cv
Complete Dulbecco’s Modified Eagles Media C Dmem 400 μm L Arginine 10–013 Cv, supplied by Cellgro, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/complete dulbecco’s modified eagles media c-dmem 400 μm l-arginine 10–013-cv/product/Cellgro
Average 90 stars, based on 1 article reviews
complete dulbecco’s modified eagles media c-dmem 400 μm l-arginine 10–013-cv - by Bioz Stars, 2026-03
90/100 stars
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complete dmem labeling media  (Cellgro)
90
Cellgro complete dmem labeling media
Complete Dmem Labeling Media, supplied by Cellgro, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/complete dmem labeling media/product/Cellgro
Average 90 stars, based on 1 article reviews
complete dmem labeling media - by Bioz Stars, 2026-03
90/100 stars
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complete endotoxin-free dmem media  (Corning Life Sciences)
90
Corning Life Sciences complete endotoxin-free dmem media
Leflunomide inhibits the de novo pyrimidine synthesis pathway in KPC cells in vitro and in vivo . (A) Schematic of the de novo pyrimidine synthesis pathway. KPC cells were treated with Gem 20nM, Leflunomide 40μM as single agents or combination in <t>DMEM</t> supplemented with 200 <t>μM</t> <t>L-Glutamine-(amide-</t> 15 N), 10% FBS and 1% Penicillin-Streptomycin. After 4hr and 24hr of treatment, cells were quenched with ice-cold solvent (40:40:20 Acetonitrile:Methanol:Water with 0.5% formic acid) and cellular metabolites were extracted. Relative isotopic enrichment of M L-Glutamine-(amide- 15 N) into Dihydroorotate (B), Carbamoyl-aspartate (C), UDP (D) and UTP (E) was measured by LC/MS-MS. (F) Level of Carbamoyl-aspartate from tumor tissues. Results from one representative experiment are presented as means ± SD, with triplicate determinations. (*) p < 0.05, (**) p < 0.005, (***) p < 0.001, and (****) p < 0.0001 by two-way ANOVA. M+0, all amides unlabeled 14 N amide and M+1, all amides labeled 15 N.
Complete Endotoxin Free Dmem Media, supplied by Corning Life Sciences, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/complete endotoxin-free dmem media/product/Corning Life Sciences
Average 90 stars, based on 1 article reviews
complete endotoxin-free dmem media - by Bioz Stars, 2026-03
90/100 stars
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complete dmem media without phenol red ph indicator  (Lonza)
90
Lonza complete dmem media without phenol red ph indicator
Leflunomide inhibits the de novo pyrimidine synthesis pathway in KPC cells in vitro and in vivo . (A) Schematic of the de novo pyrimidine synthesis pathway. KPC cells were treated with Gem 20nM, Leflunomide 40μM as single agents or combination in <t>DMEM</t> supplemented with 200 <t>μM</t> <t>L-Glutamine-(amide-</t> 15 N), 10% FBS and 1% Penicillin-Streptomycin. After 4hr and 24hr of treatment, cells were quenched with ice-cold solvent (40:40:20 Acetonitrile:Methanol:Water with 0.5% formic acid) and cellular metabolites were extracted. Relative isotopic enrichment of M L-Glutamine-(amide- 15 N) into Dihydroorotate (B), Carbamoyl-aspartate (C), UDP (D) and UTP (E) was measured by LC/MS-MS. (F) Level of Carbamoyl-aspartate from tumor tissues. Results from one representative experiment are presented as means ± SD, with triplicate determinations. (*) p < 0.05, (**) p < 0.005, (***) p < 0.001, and (****) p < 0.0001 by two-way ANOVA. M+0, all amides unlabeled 14 N amide and M+1, all amides labeled 15 N.
Complete Dmem Media Without Phenol Red Ph Indicator, supplied by Lonza, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/complete dmem media without phenol red ph indicator/product/Lonza
Average 90 stars, based on 1 article reviews
complete dmem media without phenol red ph indicator - by Bioz Stars, 2026-03
90/100 stars
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dmem complete media 11-995-073  (Fisher Scientific)
90
Fisher Scientific dmem complete media 11-995-073
Leflunomide inhibits the de novo pyrimidine synthesis pathway in KPC cells in vitro and in vivo . (A) Schematic of the de novo pyrimidine synthesis pathway. KPC cells were treated with Gem 20nM, Leflunomide 40μM as single agents or combination in <t>DMEM</t> supplemented with 200 <t>μM</t> <t>L-Glutamine-(amide-</t> 15 N), 10% FBS and 1% Penicillin-Streptomycin. After 4hr and 24hr of treatment, cells were quenched with ice-cold solvent (40:40:20 Acetonitrile:Methanol:Water with 0.5% formic acid) and cellular metabolites were extracted. Relative isotopic enrichment of M L-Glutamine-(amide- 15 N) into Dihydroorotate (B), Carbamoyl-aspartate (C), UDP (D) and UTP (E) was measured by LC/MS-MS. (F) Level of Carbamoyl-aspartate from tumor tissues. Results from one representative experiment are presented as means ± SD, with triplicate determinations. (*) p < 0.05, (**) p < 0.005, (***) p < 0.001, and (****) p < 0.0001 by two-way ANOVA. M+0, all amides unlabeled 14 N amide and M+1, all amides labeled 15 N.
Dmem Complete Media 11 995 073, supplied by Fisher Scientific, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/dmem complete media 11-995-073/product/Fisher Scientific
Average 90 stars, based on 1 article reviews
dmem complete media 11-995-073 - by Bioz Stars, 2026-03
90/100 stars
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bj complete media - dmem media cellgro #15-013-cv  (Cellgro)
90
Cellgro bj complete media - dmem media cellgro #15-013-cv
Leflunomide inhibits the de novo pyrimidine synthesis pathway in KPC cells in vitro and in vivo . (A) Schematic of the de novo pyrimidine synthesis pathway. KPC cells were treated with Gem 20nM, Leflunomide 40μM as single agents or combination in <t>DMEM</t> supplemented with 200 <t>μM</t> <t>L-Glutamine-(amide-</t> 15 N), 10% FBS and 1% Penicillin-Streptomycin. After 4hr and 24hr of treatment, cells were quenched with ice-cold solvent (40:40:20 Acetonitrile:Methanol:Water with 0.5% formic acid) and cellular metabolites were extracted. Relative isotopic enrichment of M L-Glutamine-(amide- 15 N) into Dihydroorotate (B), Carbamoyl-aspartate (C), UDP (D) and UTP (E) was measured by LC/MS-MS. (F) Level of Carbamoyl-aspartate from tumor tissues. Results from one representative experiment are presented as means ± SD, with triplicate determinations. (*) p < 0.05, (**) p < 0.005, (***) p < 0.001, and (****) p < 0.0001 by two-way ANOVA. M+0, all amides unlabeled 14 N amide and M+1, all amides labeled 15 N.
Bj Complete Media Dmem Media Cellgro #15 013 Cv, supplied by Cellgro, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/bj complete media - dmem media cellgro #15-013-cv/product/Cellgro
Average 90 stars, based on 1 article reviews
bj complete media - dmem media cellgro #15-013-cv - by Bioz Stars, 2026-03
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80ul dmem complete media  (Thermal Scientific)
90
Thermal Scientific 80ul dmem complete media
Leflunomide inhibits the de novo pyrimidine synthesis pathway in KPC cells in vitro and in vivo . (A) Schematic of the de novo pyrimidine synthesis pathway. KPC cells were treated with Gem 20nM, Leflunomide 40μM as single agents or combination in <t>DMEM</t> supplemented with 200 <t>μM</t> <t>L-Glutamine-(amide-</t> 15 N), 10% FBS and 1% Penicillin-Streptomycin. After 4hr and 24hr of treatment, cells were quenched with ice-cold solvent (40:40:20 Acetonitrile:Methanol:Water with 0.5% formic acid) and cellular metabolites were extracted. Relative isotopic enrichment of M L-Glutamine-(amide- 15 N) into Dihydroorotate (B), Carbamoyl-aspartate (C), UDP (D) and UTP (E) was measured by LC/MS-MS. (F) Level of Carbamoyl-aspartate from tumor tissues. Results from one representative experiment are presented as means ± SD, with triplicate determinations. (*) p < 0.05, (**) p < 0.005, (***) p < 0.001, and (****) p < 0.0001 by two-way ANOVA. M+0, all amides unlabeled 14 N amide and M+1, all amides labeled 15 N.
80ul Dmem Complete Media, supplied by Thermal Scientific, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/80ul dmem complete media/product/Thermal Scientific
Average 90 stars, based on 1 article reviews
80ul dmem complete media - by Bioz Stars, 2026-03
90/100 stars
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phrodo green dextran-containing complete dmem media  (Fisher Scientific)
90
Fisher Scientific phrodo green dextran-containing complete dmem media
Leflunomide inhibits the de novo pyrimidine synthesis pathway in KPC cells in vitro and in vivo . (A) Schematic of the de novo pyrimidine synthesis pathway. KPC cells were treated with Gem 20nM, Leflunomide 40μM as single agents or combination in <t>DMEM</t> supplemented with 200 <t>μM</t> <t>L-Glutamine-(amide-</t> 15 N), 10% FBS and 1% Penicillin-Streptomycin. After 4hr and 24hr of treatment, cells were quenched with ice-cold solvent (40:40:20 Acetonitrile:Methanol:Water with 0.5% formic acid) and cellular metabolites were extracted. Relative isotopic enrichment of M L-Glutamine-(amide- 15 N) into Dihydroorotate (B), Carbamoyl-aspartate (C), UDP (D) and UTP (E) was measured by LC/MS-MS. (F) Level of Carbamoyl-aspartate from tumor tissues. Results from one representative experiment are presented as means ± SD, with triplicate determinations. (*) p < 0.05, (**) p < 0.005, (***) p < 0.001, and (****) p < 0.0001 by two-way ANOVA. M+0, all amides unlabeled 14 N amide and M+1, all amides labeled 15 N.
Phrodo Green Dextran Containing Complete Dmem Media, supplied by Fisher Scientific, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/phrodo green dextran-containing complete dmem media/product/Fisher Scientific
Average 90 stars, based on 1 article reviews
phrodo green dextran-containing complete dmem media - by Bioz Stars, 2026-03
90/100 stars
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Image Search Results


Leflunomide inhibits the de novo pyrimidine synthesis pathway in KPC cells in vitro and in vivo . (A) Schematic of the de novo pyrimidine synthesis pathway. KPC cells were treated with Gem 20nM, Leflunomide 40μM as single agents or combination in DMEM supplemented with 200 μM L-Glutamine-(amide- 15 N), 10% FBS and 1% Penicillin-Streptomycin. After 4hr and 24hr of treatment, cells were quenched with ice-cold solvent (40:40:20 Acetonitrile:Methanol:Water with 0.5% formic acid) and cellular metabolites were extracted. Relative isotopic enrichment of M L-Glutamine-(amide- 15 N) into Dihydroorotate (B), Carbamoyl-aspartate (C), UDP (D) and UTP (E) was measured by LC/MS-MS. (F) Level of Carbamoyl-aspartate from tumor tissues. Results from one representative experiment are presented as means ± SD, with triplicate determinations. (*) p < 0.05, (**) p < 0.005, (***) p < 0.001, and (****) p < 0.0001 by two-way ANOVA. M+0, all amides unlabeled 14 N amide and M+1, all amides labeled 15 N.

Journal: International Journal of Biological Sciences

Article Title: Inhibition of de novo pyrimidine synthesis augments Gemcitabine induced growth inhibition in an immunocompetent model of pancreatic cancer

doi: 10.7150/ijbs.60473

Figure Lengend Snippet: Leflunomide inhibits the de novo pyrimidine synthesis pathway in KPC cells in vitro and in vivo . (A) Schematic of the de novo pyrimidine synthesis pathway. KPC cells were treated with Gem 20nM, Leflunomide 40μM as single agents or combination in DMEM supplemented with 200 μM L-Glutamine-(amide- 15 N), 10% FBS and 1% Penicillin-Streptomycin. After 4hr and 24hr of treatment, cells were quenched with ice-cold solvent (40:40:20 Acetonitrile:Methanol:Water with 0.5% formic acid) and cellular metabolites were extracted. Relative isotopic enrichment of M L-Glutamine-(amide- 15 N) into Dihydroorotate (B), Carbamoyl-aspartate (C), UDP (D) and UTP (E) was measured by LC/MS-MS. (F) Level of Carbamoyl-aspartate from tumor tissues. Results from one representative experiment are presented as means ± SD, with triplicate determinations. (*) p < 0.05, (**) p < 0.005, (***) p < 0.001, and (****) p < 0.0001 by two-way ANOVA. M+0, all amides unlabeled 14 N amide and M+1, all amides labeled 15 N.

Article Snippet: KPC cells were grown at 37 °C, 5% CO 2 atmosphere in complete endotoxin-free DMEM media (Corning, USA) containing high glucose and glutamine supplemented with 10% FBS (Gibco, USA) and 1% penicillin and streptomycin (Gibco, USA).

Techniques: In Vitro, In Vivo, Solvent, Liquid Chromatography with Mass Spectroscopy, Labeling